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Involvement of the RAS/MAPK pathway not only increases predisposition to develop tumours, but also determines the presence of phenotypic anomalies and alterations in learning processes.

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: The term 'RASopathies' covers a series of diseases that present mutations in the genes that code for the proteins of the RAS/MAPK pathway.

These diseases include neurofibromatosis type 1, Noonan syndrome, Legius syndrome, LEOPARD syndrome, Costello syndrome and cardiofaciocutaneous syndrome.

ABSTRACT: In 1945, within the frame of the Uranium Project for the production of nuclear weapons, the Mayak nuclear facilities were constructed at the Lake Irtyash in the Southern Urals, Russia.

The nuclear workers of the Mayak Production Association (MPA), who lived in the city of Ozyorsk, are the focus of epidemiological studies for the assessment of health risks due to protracted exposure to ionising radiation.

Separately, Grindr was crowned the winner of the 2012 i Date Awards in two of the 12 categories for Best Mobile Dating App and Best New Technology at the ninth annual Dating Industry & Internet Dating Conference in Miami.

If you’ve been single for a while it can be all too easy to view tales of lasting love and marriage as some sort of urban relationship myth, meant only for the very handsome, the very rich or the very lucky!We report the case of a 12-year-old patient with some of the abovementioned characteristics: hypertelorism, macroglossia, lentigines, hypospadias, cryptorchidism, subaortic stenosis, growth retardation, and hearing impairment.Due to this set of symptoms, we diagnosed Leopard syndrome.The unknown dose is obtained by subtracting a mean native dose from the back-extrapolated dose.As an example of the capability of the ISS protocol in unknown dose evaluation, the results obtained in the framework of the 2nd International Intercomparison on EPR tooth enamel dosimetry are reported.Lashawn Johnson, who was already in jail on unrelated charges, was charged with her murder on Sunday, the station reports."You go to sleep with different pain but at least, we've gone searching for her so many times."Russo's cause of death hasn't yet been released.

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